Tracer kinetic assessment of blood–brain barrier leakage and blood volume in cerebral small vessel disease: Associations with disease burden and vascular risk factors

Tracer kinetic assessment of blood–brain barrier leakage and blood volume in cerebral small vessel disease: Associations with disease burden and vascular risk factors

Subtle blood–brain barrier (BBB) permeability increases have been shown in small vessel disease (SVD) using various analysis methods. Following recent consensus recommendations, we used Patlak tracer kinetic analysis, considered optimal in low permeability states, to quantify permeability-surface ar...

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Bibliographic Details
Main Authors: Michael S. Stringer, Anna K. Heye, Paul A. Armitage, Francesca Chappell, Maria del C. Valdés Hernández, Stephen D.J. Makin, Eleni Sakka, Michael J. Thrippleton, Joanna M. Wardlaw
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Blood brain barrier
Cerebrovascular disease
MRI
Stroke
SVD
Computer applications to medicine. Medical informatics
R858-859.7
Neurology. Diseases of the nervous system
RC346-429
Online Access:https://doaj.org/article/f635bc0137e744758b0076d27a555a86
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https://doaj.org/article/f635bc0137e744758b0076d27a555a86

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