Tracer kinetic assessment of blood–brain barrier leakage and blood volume in cerebral small vessel disease: Associations with disease burden and vascular risk factors

Subtle blood–brain barrier (BBB) permeability increases have been shown in small vessel disease (SVD) using various analysis methods. Following recent consensus recommendations, we used Patlak tracer kinetic analysis, considered optimal in low permeability states, to quantify permeability-surface ar...

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Autores principales: Michael S. Stringer, Anna K. Heye, Paul A. Armitage, Francesca Chappell, Maria del C. Valdés Hernández, Stephen D.J. Makin, Eleni Sakka, Michael J. Thrippleton, Joanna M. Wardlaw
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
MRI
SVD
Acceso en línea:https://doaj.org/article/f635bc0137e744758b0076d27a555a86
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