Involvement of classic and alternative non-homologous end joining pathways in hematologic malignancies: targeting strategies for treatment
Abstract Chromosomal translocations are the main etiological factor of hematologic malignancies. These translocations are generally the consequence of aberrant DNA double-strand break (DSB) repair. DSBs arise either exogenously or endogenously in cells and are repaired by major pathways, including n...
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Autores principales: | , , , , |
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Formato: | article |
Lenguaje: | EN |
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BMC
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/f65821dddac94eee87c69283e2a72504 |
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