Development of in situ gelling and bio adhesive 5-Fluorouracil enema.

In this study, a novel 5-Fluorouracil (5-FU) enema with good bio adhesion and temperature sensitivity was developed using in situ gelling technology. The preparation was formulated as a free-flowing liquid before use, while a layer of gel film was quickly formed when administered in the rectum, with...

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Autores principales: Lu-Lu Wang, Wen-Sheng Zheng, Shao-Hua Chen, Xia-Qin Fang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/f679d261cae942fd8ac0d803fd845262
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