The histone demethylase JMJD2A/KDM4A links ribosomal RNA transcription to nutrients and growth factors availability
Histone methylation regulates gene expression. Here, Salifou et al.show that KDM4A, a histone lysine demethylase, regulates RNA polymerase I-driven transcription in a PI3K dependent manner, therefore linking nutrients and growth factors availability to ribosomal RNA transcription.
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| Main Authors: | , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2016
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| Subjects: | |
| Online Access: | https://doaj.org/article/f68c012eaa2d4999844a9ef3bbf50a85 |
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