The histone demethylase JMJD2A/KDM4A links ribosomal RNA transcription to nutrients and growth factors availability

The histone demethylase JMJD2A/KDM4A links ribosomal RNA transcription to nutrients and growth factors availability

Histone methylation regulates gene expression. Here, Salifou et al.show that KDM4A, a histone lysine demethylase, regulates RNA polymerase I-driven transcription in a PI3K dependent manner, therefore linking nutrients and growth factors availability to ribosomal RNA transcription.

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Detalles Bibliográficos
Autores principales: Kader Salifou, Swagat Ray, Laure Verrier, Marion Aguirrebengoa, Didier Trouche, Konstantin I. Panov, Marie Vandromme
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/f68c012eaa2d4999844a9ef3bbf50a85
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