Large-scale network analysis reveals the sequence space architecture of antibody repertoires

Analysis of large-scale immune repertoire architecture remains a challenge. Here, the authors introduce an approach to construct similarity networks from high-throughput antibody repertoire sequencing data, and show that the networks are redundant, robust and reproducible across individuals.

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Autores principales: Enkelejda Miho, Rok Roškar, Victor Greiff, Sai T. Reddy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/f6972148747046a6ac850662095375ec
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