Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum
The most advanced P. falciparum circumsporozoite protein (PfCSP)-based malaria vaccine confers partial protection. Here, Pholcharee et al. present crystal structures, binding affinities/kinetics, and in vivo protection of 8 anti-NANP antibodies to understand in vivo protection of PfCSP-targeting ant...
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Main Authors: | Tossapol Pholcharee, David Oyen, Yevel Flores-Garcia, Gonzalo Gonzalez-Paez, Zhen Han, Katherine L. Williams, Wayne Volkmuth, Daniel Emerling, Emily Locke, C. Richter King, Fidel Zavala, Ian A. Wilson |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/f69e762087b34c9ba0a1c8a3d1c005e9 |
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