Advancement of pharmacokinetic models of iohexol in patients aged 70 years or older with impaired kidney function

Abstract Plasma clearance of iohexol is a pivotal metric to quantify glomerular filtration rate (GFR), but the optimal timing and frequency of plasma sampling remain to be assessed. In this study, we evaluated the impact of a Bayesian estimation procedure on iohexol clearance estimates, and we ident...

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Bibliographic Details
Main Authors: Max Taubert, Elke Schaeffner, Peter Martus, Markus van der Giet, Uwe Fuhr, Amina Lösment, Natalie Ebert
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/f6a1f16dee5843c097c784d47edb7de6
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