A Single Native Ganglioside GM<sub>1</sub>-Binding Site Is Sufficient for Cholera Toxin To Bind to Cells and Complete the Intoxication Pathway
ABSTRACT Cholera toxin (CT) from Vibrio cholerae is responsible for the majority of the symptoms of the diarrheal disease cholera. CT is a heterohexameric protein complex with a 240-residue A subunit and a pentameric B subunit of identical 103-residue B polypeptides. The A subunit is proteolytically...
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| Auteurs principaux: | , , , , |
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| Format: | article |
| Langue: | EN |
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American Society for Microbiology
2012
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| Accès en ligne: | https://doaj.org/article/f6b94cc25bd8432ba19d50729f26c1eb |
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