Targeting eIF4F translation complex sensitizes B-ALL cells to tyrosine kinase inhibition
Abstract The mechanistic target of rapamycin (mTOR) is a kinase whose activation is associated with poor prognosis in pre-B cell acute lymphoblastic leukemia (B-ALL). These and other findings have prompted diverse strategies for targeting mTOR signaling in B-ALL and other B-cell malignancies. In cel...
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Auteurs principaux: | , , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/f6da06c10adf41ed853a873822db0706 |
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