Critical role of CD4+ T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection

Critical role of CD4+ T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection

Characterization of protective immunity to Zika virus has largely focussed on CD8+ T cells and antibody-mediated protection. Here the authors show roles for CD4+ T cells and the associated IFNγ signaling in antibody-mediated resistance to Zika virus infection.

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Autores principales: Carolina G. O. Lucas, Jamil Z. Kitoko, Fabricio M. Ferreira, Vinicius G. Suzart, Michelle P. Papa, Sharton V. A. Coelho, Cecilia B. Cavazzoni, Heitor A. Paula-Neto, Priscilla C. Olsen, Akiko Iwasaki, Renata M. Pereira, Pedro M. Pimentel-Coelho, Andre M. Vale, Luciana B. de Arruda, Marcelo T. Bozza
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
Q
Acceso en línea:https://doaj.org/article/f7026cc58b4043d2934f510dfe446fd8
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https://doaj.org/article/f7026cc58b4043d2934f510dfe446fd8

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