Critical role of CD4+ T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection

Characterization of protective immunity to Zika virus has largely focussed on CD8+ T cells and antibody-mediated protection. Here the authors show roles for CD4+ T cells and the associated IFNγ signaling in antibody-mediated resistance to Zika virus infection.

Guardado en:

Detalles Bibliográficos
Autores principales:	Carolina G. O. Lucas, Jamil Z. Kitoko, Fabricio M. Ferreira, Vinicius G. Suzart, Michelle P. Papa, Sharton V. A. Coelho, Cecilia B. Cavazzoni, Heitor A. Paula-Neto, Priscilla C. Olsen, Akiko Iwasaki, Renata M. Pereira, Pedro M. Pimentel-Coelho, Andre M. Vale, Luciana B. de Arruda, Marcelo T. Bozza
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f7026cc58b4043d2934f510dfe446fd8
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f7026cc58b4043d2934f510dfe446fd8
record_format	dspace
spelling	oai:doaj.org-article:f7026cc58b4043d2934f510dfe446fd82021-12-02T17:31:43ZCritical role of CD4+ T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection10.1038/s41467-018-05519-42041-1723https://doaj.org/article/f7026cc58b4043d2934f510dfe446fd82018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05519-4https://doaj.org/toc/2041-1723Characterization of protective immunity to Zika virus has largely focussed on CD8+ T cells and antibody-mediated protection. Here the authors show roles for CD4+ T cells and the associated IFNγ signaling in antibody-mediated resistance to Zika virus infection.Carolina G. O. LucasJamil Z. KitokoFabricio M. FerreiraVinicius G. SuzartMichelle P. PapaSharton V. A. CoelhoCecilia B. CavazzoniHeitor A. Paula-NetoPriscilla C. OlsenAkiko IwasakiRenata M. PereiraPedro M. Pimentel-CoelhoAndre M. ValeLuciana B. de ArrudaMarcelo T. BozzaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Carolina G. O. Lucas Jamil Z. Kitoko Fabricio M. Ferreira Vinicius G. Suzart Michelle P. Papa Sharton V. A. Coelho Cecilia B. Cavazzoni Heitor A. Paula-Neto Priscilla C. Olsen Akiko Iwasaki Renata M. Pereira Pedro M. Pimentel-Coelho Andre M. Vale Luciana B. de Arruda Marcelo T. Bozza Critical role of CD4+ T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection
description	Characterization of protective immunity to Zika virus has largely focussed on CD8+ T cells and antibody-mediated protection. Here the authors show roles for CD4+ T cells and the associated IFNγ signaling in antibody-mediated resistance to Zika virus infection.
format	article
author	Carolina G. O. Lucas Jamil Z. Kitoko Fabricio M. Ferreira Vinicius G. Suzart Michelle P. Papa Sharton V. A. Coelho Cecilia B. Cavazzoni Heitor A. Paula-Neto Priscilla C. Olsen Akiko Iwasaki Renata M. Pereira Pedro M. Pimentel-Coelho Andre M. Vale Luciana B. de Arruda Marcelo T. Bozza
author_facet	Carolina G. O. Lucas Jamil Z. Kitoko Fabricio M. Ferreira Vinicius G. Suzart Michelle P. Papa Sharton V. A. Coelho Cecilia B. Cavazzoni Heitor A. Paula-Neto Priscilla C. Olsen Akiko Iwasaki Renata M. Pereira Pedro M. Pimentel-Coelho Andre M. Vale Luciana B. de Arruda Marcelo T. Bozza
author_sort	Carolina G. O. Lucas
title	Critical role of CD4+ T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection
title_short	Critical role of CD4+ T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection
title_full	Critical role of CD4+ T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection
title_fullStr	Critical role of CD4+ T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection
title_full_unstemmed	Critical role of CD4+ T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection
title_sort	critical role of cd4+ t cells and ifnγ signaling in antibody-mediated resistance to zika virus infection
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f7026cc58b4043d2934f510dfe446fd8
work_keys_str_mv	AT carolinagolucas criticalroleofcd4tcellsandifngsignalinginantibodymediatedresistancetozikavirusinfection AT jamilzkitoko criticalroleofcd4tcellsandifngsignalinginantibodymediatedresistancetozikavirusinfection AT fabriciomferreira criticalroleofcd4tcellsandifngsignalinginantibodymediatedresistancetozikavirusinfection AT viniciusgsuzart criticalroleofcd4tcellsandifngsignalinginantibodymediatedresistancetozikavirusinfection AT michelleppapa criticalroleofcd4tcellsandifngsignalinginantibodymediatedresistancetozikavirusinfection AT shartonvacoelho criticalroleofcd4tcellsandifngsignalinginantibodymediatedresistancetozikavirusinfection AT ceciliabcavazzoni criticalroleofcd4tcellsandifngsignalinginantibodymediatedresistancetozikavirusinfection AT heitorapaulaneto criticalroleofcd4tcellsandifngsignalinginantibodymediatedresistancetozikavirusinfection AT priscillacolsen criticalroleofcd4tcellsandifngsignalinginantibodymediatedresistancetozikavirusinfection AT akikoiwasaki criticalroleofcd4tcellsandifngsignalinginantibodymediatedresistancetozikavirusinfection AT renatampereira criticalroleofcd4tcellsandifngsignalinginantibodymediatedresistancetozikavirusinfection AT pedrompimentelcoelho criticalroleofcd4tcellsandifngsignalinginantibodymediatedresistancetozikavirusinfection AT andremvale criticalroleofcd4tcellsandifngsignalinginantibodymediatedresistancetozikavirusinfection AT lucianabdearruda criticalroleofcd4tcellsandifngsignalinginantibodymediatedresistancetozikavirusinfection AT marcelotbozza criticalroleofcd4tcellsandifngsignalinginantibodymediatedresistancetozikavirusinfection
_version_	1718380529985781760

Critical role of CD4+ T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection

Ejemplares similares