QNBC Is Associated with High Genomic Instability Characterized by Copy Number Alterations and miRNA Deregulation

QNBC Is Associated with High Genomic Instability Characterized by Copy Number Alterations and miRNA Deregulation

Triple-negative breast cancer (TNBC) can be further classified into androgen receptor (AR)-positive TNBC and AR-negative TNBC or quadruple-negative breast cancer (QNBC). Here, we investigated genomic instability in 53 clinical cases by array-CGH and miRNA expression profiling. Immunohistochemical an...

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Autores principales: Shristi Bhattarai, Bruna M. Sugita, Stefanne M. Bortoletto, Aline S. Fonseca, Luciane R. Cavalli, Ritu Aneja
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
triple-negative breast cancer
quadruple-negative breast cancer
AR loss
genomic instability
copy number
array-CGH
Biology (General)
QH301-705.5
Chemistry
QD1-999
Acceso en línea:https://doaj.org/article/f71df66240004edba2369d048b0f563a
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https://doaj.org/article/f71df66240004edba2369d048b0f563a

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