Competition between crystal and fibril formation in molecular mutations of amyloidogenic peptides

Aggregation of amyloidogenic peptides into fibrils and crystals has incidence in several amyloid-related diseases. Here, the authors investigate the origins of the fibril-to-crystal conversion in amyloidogenic hexapeptides pointing to the amyloid crystals as the ground state in the protein folding e...

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Bibliographic Details
Main Authors: Nicholas P. Reynolds, Jozef Adamcik, Joshua T. Berryman, Stephan Handschin, Ali Asghar Hakami Zanjani, Wen Li, Kun Liu, Afang Zhang, Raffaele Mezzenga
Format: article
Language:EN
Published: Nature Portfolio 2017
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Q
Online Access:https://doaj.org/article/f724699c0cff4d61b17cab20071aad41
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