Engineering orthogonal dual transcription factors for multi-input synthetic promoters

Genetic circuits usually employ the same set of transcription factors which can act via repression or activation of the target promoter. Here the authors present dual activator-repressor switches, designed via directed evolution, for orthogonal logic gates and multi-input circuit architectures.

Guardado en:

Detalles Bibliográficos
Autores principales:	Andreas K. Brödel, Alfonso Jaramillo, Mark Isalan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f72dc6142a374e1c9bf71d80e2e3a5fe
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f72dc6142a374e1c9bf71d80e2e3a5fe
record_format	dspace
spelling	oai:doaj.org-article:f72dc6142a374e1c9bf71d80e2e3a5fe2021-12-02T17:31:18ZEngineering orthogonal dual transcription factors for multi-input synthetic promoters10.1038/ncomms138582041-1723https://doaj.org/article/f72dc6142a374e1c9bf71d80e2e3a5fe2016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13858https://doaj.org/toc/2041-1723Genetic circuits usually employ the same set of transcription factors which can act via repression or activation of the target promoter. Here the authors present dual activator-repressor switches, designed via directed evolution, for orthogonal logic gates and multi-input circuit architectures.Andreas K. BrödelAlfonso JaramilloMark IsalanNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Andreas K. Brödel Alfonso Jaramillo Mark Isalan Engineering orthogonal dual transcription factors for multi-input synthetic promoters
description	Genetic circuits usually employ the same set of transcription factors which can act via repression or activation of the target promoter. Here the authors present dual activator-repressor switches, designed via directed evolution, for orthogonal logic gates and multi-input circuit architectures.
format	article
author	Andreas K. Brödel Alfonso Jaramillo Mark Isalan
author_facet	Andreas K. Brödel Alfonso Jaramillo Mark Isalan
author_sort	Andreas K. Brödel
title	Engineering orthogonal dual transcription factors for multi-input synthetic promoters
title_short	Engineering orthogonal dual transcription factors for multi-input synthetic promoters
title_full	Engineering orthogonal dual transcription factors for multi-input synthetic promoters
title_fullStr	Engineering orthogonal dual transcription factors for multi-input synthetic promoters
title_full_unstemmed	Engineering orthogonal dual transcription factors for multi-input synthetic promoters
title_sort	engineering orthogonal dual transcription factors for multi-input synthetic promoters
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/f72dc6142a374e1c9bf71d80e2e3a5fe
work_keys_str_mv	AT andreaskbrodel engineeringorthogonaldualtranscriptionfactorsformultiinputsyntheticpromoters AT alfonsojaramillo engineeringorthogonaldualtranscriptionfactorsformultiinputsyntheticpromoters AT markisalan engineeringorthogonaldualtranscriptionfactorsformultiinputsyntheticpromoters
_version_	1718380709753651200

Engineering orthogonal dual transcription factors for multi-input synthetic promoters

Ejemplares similares