Engineering orthogonal dual transcription factors for multi-input synthetic promoters
Genetic circuits usually employ the same set of transcription factors which can act via repression or activation of the target promoter. Here the authors present dual activator-repressor switches, designed via directed evolution, for orthogonal logic gates and multi-input circuit architectures.
Guardado en:
Autores principales: | Andreas K. Brödel, Alfonso Jaramillo, Mark Isalan |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f72dc6142a374e1c9bf71d80e2e3a5fe |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Dual-Input and Multi-Channel Convolutional Neural Network Model for Vehicle Speed Prediction
por: Jiaming Xing, et al.
Publicado: (2021) -
Bacterial encapsulins as orthogonal compartments for mammalian cell engineering
por: Felix Sigmund, et al.
Publicado: (2018) -
Orthogonal translation enables heterologous ribosome engineering in E. coli
por: Natalie S. Kolber, et al.
Publicado: (2021) -
Transcription Factors in Alkaloid Engineering
por: Yasuyuki Yamada, et al.
Publicado: (2021) -
Modulating mechanical stability of heterodimerization between engineered orthogonal helical domains
por: Miao Yu, et al.
Publicado: (2020)