Reactive oxygen species regulate caspase-11 expression and activation of the non-canonical NLRP3 inflammasome during enteric pathogen infection.

Enteropathogenic and enterohemorrhagic bacterial infections in humans are a severe cause of morbidity and mortality. Although NOD-like receptors (NLRs) NOD2 and NLRP3 have important roles in the generation of protective immune responses to enteric pathogens, whether there is crosstalk among NLRs to...

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Autores principales: Christopher R Lupfer, Paras K Anand, Zhiping Liu, Kate L Stokes, Peter Vogel, Mohamed Lamkanfi, Thirumala-Devi Kanneganti
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/f768b574929e431d8ad7267be7bc15c6
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