Reactive oxygen species regulate caspase-11 expression and activation of the non-canonical NLRP3 inflammasome during enteric pathogen infection.
Enteropathogenic and enterohemorrhagic bacterial infections in humans are a severe cause of morbidity and mortality. Although NOD-like receptors (NLRs) NOD2 and NLRP3 have important roles in the generation of protective immune responses to enteric pathogens, whether there is crosstalk among NLRs to...
Guardado en:
Autores principales: | Christopher R Lupfer, Paras K Anand, Zhiping Liu, Kate L Stokes, Peter Vogel, Mohamed Lamkanfi, Thirumala-Devi Kanneganti |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/f768b574929e431d8ad7267be7bc15c6 |
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