A role for polyploidy in the tumorigenicity of Pim-1-expressing human prostate and mammary epithelial cells.

<h4>Background</h4>Polyploidy is a prominent feature of many human cancers, and it has long been hypothesized that polyploidy may contribute to tumorigenesis by promoting genomic instability. In this study, we investigated whether polyploidy per se induced by a relevant oncogene can prom...

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Auteurs principaux: Meejeon Roh, Omar E Franco, Simon W Hayward, Riet van der Meer, Sarki A Abdulkadir
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2008
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R
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Accès en ligne:https://doaj.org/article/f7c3d302cc6643d9942ab3d9f8a02b8d
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