Multifunctional cationic nanosystems for nucleic acid therapy of thoracic aortic dissection
Thoracic aortic dissection has a high fatality rate and no effective treatment. Here, the authors develop cationic nanoparticles for the delivery of miR-145 and show that they stabilize vascular structures and prevent further deterioration of the aorta in mouse models of the disease.
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2019
|
| Subjects: | |
| Online Access: | https://doaj.org/article/f7cf82f1599a4b6b86b79b2f7774664c |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|