Multifunctional cationic nanosystems for nucleic acid therapy of thoracic aortic dissection
Thoracic aortic dissection has a high fatality rate and no effective treatment. Here, the authors develop cationic nanoparticles for the delivery of miR-145 and show that they stabilize vascular structures and prevent further deterioration of the aorta in mouse models of the disease.
Guardado en:
Autores principales: | Chen Xu, Yanzhenzi Zhang, Ke Xu, Jing-Jun Nie, Bingran Yu, Sijin Li, Gang Cheng, Yulin Li, Jie Du, Fu-Jian Xu |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f7cf82f1599a4b6b86b79b2f7774664c |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Aortic remodeling in Type B aortic dissection after thoracic endovascular aortic repair with an aortic extender cuff implantation
por: Zhang H, et al.
Publicado: (2018) -
Genetic testing and clinical relevance of patients with thoracic aortic aneurysm and dissection in northwestern China
por: Jinjie Li, et al.
Publicado: (2021) -
Incidence, Predictors and Outcomes of Delirium in Complicated Type B Aortic Dissection Patients After Thoracic Endovascular Aortic Repair
por: Liu J, et al.
Publicado: (2021) -
Multifunctional nanosystems: growing sanguinity in siRNA therapy
por: Badrealam KF, et al.
Publicado: (2014) -
Multifunctional Mitochondria-Targeting Nanosystems for Enhanced Anticancer Efficacy
por: Tingting Hu, et al.
Publicado: (2021)