Human mitochondrial pyruvate carrier 2 as an autonomous membrane transporter
Abstract The active transport of glycolytic pyruvate across the inner mitochondrial membrane is thought to involve two mitochondrial pyruvate carrier subunits, MPC1 and MPC2, assembled as a 150 kDa heterotypic oligomer. Here, the recombinant production of human MPC through a co-expression strategy i...
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Auteurs principaux: | , , , , , , , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
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Accès en ligne: | https://doaj.org/article/f7dc7c92e807412e8c44de0a8d8ff413 |
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