Insight into the mechanisms of adenovirus capsid disassembly from studies of defensin neutralization.

Defensins are effectors of the innate immune response with potent antibacterial activity. Their role in antiviral immunity, particularly for non-enveloped viruses, is poorly understood. We recently found that human alpha-defensins inhibit human adenovirus (HAdV) by preventing virus uncoating and rel...

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Auteurs principaux: Jason G Smith, Mariena Silvestry, Steffen Lindert, Wuyuan Lu, Glen R Nemerow, Phoebe L Stewart
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2010
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Accès en ligne:https://doaj.org/article/f8303a732833465089b6356b5079e7a6
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