Oxidative damage-induced hyperactive ribosome biogenesis participates in tumorigenesis of offspring by cross-interacting with the Wnt and TGF-β1 pathways in IVF embryos

IVF: Mechanism and correction of increased cancer risk Increased production of ribosomes, the multi-molecular structures inside cells where protein synthesis occurs, is implicated in the enhanced risk of cancer in offspring conceived by in vitro fertilization (IVF), suggesting an approach to reduce...

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Auteurs principaux: Yue Huang, Zhiling Li, En Lin, Pei He, Gaizhen Ru
Format: article
Langue:EN
Publié: Nature Publishing Group 2021
Sujets:
R
Accès en ligne:https://doaj.org/article/f84694a74b4645d9954964ac38c1c111
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