A novel measure of chromosome instability can account for prognostic difference in multiple myeloma.

Multiple myeloma (MM) is characterized by complex genetic abnormalities whose complexity signifies varying degree of chromosomal instability (CIN). In this study, we introduced a novel CIN measure, chromosome instability genome event count (CINGEC), which considered both copy number aberrations and...

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Auteurs principaux: Tae-Hoon Chung, George Mulligan, Rafael Fonseca, Wee Joo Chng
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/f85a0564af5e41f999abd3cb5d8d4469
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