A novel measure of chromosome instability can account for prognostic difference in multiple myeloma.

Multiple myeloma (MM) is characterized by complex genetic abnormalities whose complexity signifies varying degree of chromosomal instability (CIN). In this study, we introduced a novel CIN measure, chromosome instability genome event count (CINGEC), which considered both copy number aberrations and...

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Autores principales: Tae-Hoon Chung, George Mulligan, Rafael Fonseca, Wee Joo Chng
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/f85a0564af5e41f999abd3cb5d8d4469
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