Collagen fiber regulation in human pediatric aortic valve development and disease

Abstract Congenital aortic valve stenosis (CAVS) affects up to 10% of the world population without medical therapies to treat the disease. New molecular targets are continually being sought that can halt CAVS progression. Collagen deregulation is a hallmark of CAVS yet remains mostly undefined. Here...

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Auteurs principaux: Cassandra L. Clift, Yan Ru Su, David Bichell, Heather C. Jensen Smith, Jennifer R. Bethard, Kim Norris-Caneda, Susana Comte-Walters, Lauren E. Ball, M. A. Hollingsworth, Anand S. Mehta, Richard R. Drake, Peggi M. Angel
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/f870ac3e8279454988ad55f7c7a0b959
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