ATP-dependent modulation of MgtE in Mg2+ homeostasis

ATP-dependent modulation of MgtE in Mg2+ homeostasis

Author summary MgtE is an Mg2+ transporter involved in Mg2+ homeostasis. Here, the authors report that ATP regulates the Mg+2-dependent gating of MgtE and use X-ray crystallography combined with functional studies to propose the molecular mechanisms involved in this process.

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Autores principales: Atsuhiro Tomita, Mingfeng Zhang, Fei Jin, Wenhui Zhuang, Hironori Takeda, Tatsuro Maruyama, Masanori Osawa, Ken-ichi Hashimoto, Hisashi Kawasaki, Koichi Ito, Naoshi Dohmae, Ryuichiro Ishitani, Ichio Shimada, Zhiqiang Yan, Motoyuki Hattori, Osamu Nureki
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
Q
Acceso en línea:https://doaj.org/article/f888e0a3dea7456dbdf43ae0cd85611d
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spelling oai:doaj.org-article:f888e0a3dea7456dbdf43ae0cd85611d2021-12-02T13:57:54ZATP-dependent modulation of MgtE in Mg2+ homeostasis10.1038/s41467-017-00082-w2041-1723https://doaj.org/article/f888e0a3dea7456dbdf43ae0cd85611d2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00082-whttps://doaj.org/toc/2041-1723Author summary MgtE is an Mg2+ transporter involved in Mg2+ homeostasis. Here, the authors report that ATP regulates the Mg+2-dependent gating of MgtE and use X-ray crystallography combined with functional studies to propose the molecular mechanisms involved in this process.Atsuhiro TomitaMingfeng ZhangFei JinWenhui ZhuangHironori TakedaTatsuro MaruyamaMasanori OsawaKen-ichi HashimotoHisashi KawasakiKoichi ItoNaoshi DohmaeRyuichiro IshitaniIchio ShimadaZhiqiang YanMotoyuki HattoriOsamu NurekiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Atsuhiro Tomita
Mingfeng Zhang
Fei Jin
Wenhui Zhuang
Hironori Takeda
Tatsuro Maruyama
Masanori Osawa
Ken-ichi Hashimoto
Hisashi Kawasaki
Koichi Ito
Naoshi Dohmae
Ryuichiro Ishitani
Ichio Shimada
Zhiqiang Yan
Motoyuki Hattori
Osamu Nureki
ATP-dependent modulation of MgtE in Mg2+ homeostasis
description Author summary MgtE is an Mg2+ transporter involved in Mg2+ homeostasis. Here, the authors report that ATP regulates the Mg+2-dependent gating of MgtE and use X-ray crystallography combined with functional studies to propose the molecular mechanisms involved in this process.
format article
author Atsuhiro Tomita
Mingfeng Zhang
Fei Jin
Wenhui Zhuang
Hironori Takeda
Tatsuro Maruyama
Masanori Osawa
Ken-ichi Hashimoto
Hisashi Kawasaki
Koichi Ito
Naoshi Dohmae
Ryuichiro Ishitani
Ichio Shimada
Zhiqiang Yan
Motoyuki Hattori
Osamu Nureki
author_facet Atsuhiro Tomita
Mingfeng Zhang
Fei Jin
Wenhui Zhuang
Hironori Takeda
Tatsuro Maruyama
Masanori Osawa
Ken-ichi Hashimoto
Hisashi Kawasaki
Koichi Ito
Naoshi Dohmae
Ryuichiro Ishitani
Ichio Shimada
Zhiqiang Yan
Motoyuki Hattori
Osamu Nureki
author_sort Atsuhiro Tomita
title ATP-dependent modulation of MgtE in Mg2+ homeostasis
title_short ATP-dependent modulation of MgtE in Mg2+ homeostasis
title_full ATP-dependent modulation of MgtE in Mg2+ homeostasis
title_fullStr ATP-dependent modulation of MgtE in Mg2+ homeostasis
title_full_unstemmed ATP-dependent modulation of MgtE in Mg2+ homeostasis
title_sort atp-dependent modulation of mgte in mg2+ homeostasis
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/f888e0a3dea7456dbdf43ae0cd85611d
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