Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation

Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation

Novofumigatonin is a meroterpenoid found in the fungus Aspergillus novofumigatus. Here, the authors elucidate the biosynthetic pathway of novofumigatonin and show that the endoperoxidase NvfI and the endoperoxide isomerase NvfE are involved in it.

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Autores principales: Yudai Matsuda, Tongxuan Bai, Christopher B. W. Phippen, Christina S. Nødvig, Inge Kjærbølling, Tammi C. Vesth, Mikael R. Andersen, Uffe H. Mortensen, Charlotte H. Gotfredsen, Ikuro Abe, Thomas O. Larsen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f8bace992a6e4e60b67bdc7a558f216d
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spelling oai:doaj.org-article:f8bace992a6e4e60b67bdc7a558f216d2021-12-02T14:39:45ZNovofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation10.1038/s41467-018-04983-22041-1723https://doaj.org/article/f8bace992a6e4e60b67bdc7a558f216d2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04983-2https://doaj.org/toc/2041-1723Novofumigatonin is a meroterpenoid found in the fungus Aspergillus novofumigatus. Here, the authors elucidate the biosynthetic pathway of novofumigatonin and show that the endoperoxidase NvfI and the endoperoxide isomerase NvfE are involved in it.Yudai MatsudaTongxuan BaiChristopher B. W. PhippenChristina S. NødvigInge KjærbøllingTammi C. VesthMikael R. AndersenUffe H. MortensenCharlotte H. GotfredsenIkuro AbeThomas O. LarsenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yudai Matsuda
Tongxuan Bai
Christopher B. W. Phippen
Christina S. Nødvig
Inge Kjærbølling
Tammi C. Vesth
Mikael R. Andersen
Uffe H. Mortensen
Charlotte H. Gotfredsen
Ikuro Abe
Thomas O. Larsen
Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation
description Novofumigatonin is a meroterpenoid found in the fungus Aspergillus novofumigatus. Here, the authors elucidate the biosynthetic pathway of novofumigatonin and show that the endoperoxidase NvfI and the endoperoxide isomerase NvfE are involved in it.
format article
author Yudai Matsuda
Tongxuan Bai
Christopher B. W. Phippen
Christina S. Nødvig
Inge Kjærbølling
Tammi C. Vesth
Mikael R. Andersen
Uffe H. Mortensen
Charlotte H. Gotfredsen
Ikuro Abe
Thomas O. Larsen
author_facet Yudai Matsuda
Tongxuan Bai
Christopher B. W. Phippen
Christina S. Nødvig
Inge Kjærbølling
Tammi C. Vesth
Mikael R. Andersen
Uffe H. Mortensen
Charlotte H. Gotfredsen
Ikuro Abe
Thomas O. Larsen
author_sort Yudai Matsuda
title Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation
title_short Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation
title_full Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation
title_fullStr Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation
title_full_unstemmed Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation
title_sort novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/f8bace992a6e4e60b67bdc7a558f216d
work_keys_str_mv AT yudaimatsuda novofumigatoninbiosynthesisinvolvesanonhemeirondependentendoperoxideisomerasefororthoesterformation
AT tongxuanbai novofumigatoninbiosynthesisinvolvesanonhemeirondependentendoperoxideisomerasefororthoesterformation
AT christopherbwphippen novofumigatoninbiosynthesisinvolvesanonhemeirondependentendoperoxideisomerasefororthoesterformation
AT christinasnødvig novofumigatoninbiosynthesisinvolvesanonhemeirondependentendoperoxideisomerasefororthoesterformation
AT ingekjærbølling novofumigatoninbiosynthesisinvolvesanonhemeirondependentendoperoxideisomerasefororthoesterformation
AT tammicvesth novofumigatoninbiosynthesisinvolvesanonhemeirondependentendoperoxideisomerasefororthoesterformation
AT mikaelrandersen novofumigatoninbiosynthesisinvolvesanonhemeirondependentendoperoxideisomerasefororthoesterformation
AT uffehmortensen novofumigatoninbiosynthesisinvolvesanonhemeirondependentendoperoxideisomerasefororthoesterformation
AT charlottehgotfredsen novofumigatoninbiosynthesisinvolvesanonhemeirondependentendoperoxideisomerasefororthoesterformation
AT ikuroabe novofumigatoninbiosynthesisinvolvesanonhemeirondependentendoperoxideisomerasefororthoesterformation
AT thomasolarsen novofumigatoninbiosynthesisinvolvesanonhemeirondependentendoperoxideisomerasefororthoesterformation
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