Aminoacyl sulfonamide assembly in SB-203208 biosynthesis

por Zhijuan Hu, Takayoshi Awakawa, Zhongjun Ma, Ikuro Abe
Publicado 2019

Molecular insights into the endoperoxide formation by Fe(II)/α-KG-dependent oxygenase NvfI

por Takahiro Mori, Rui Zhai, Richiro Ushimaru, Yudai Matsuda, Ikuro Abe
Publicado 2021

Manipulation of prenylation reactions by structure-based engineering of bacterial indolactam prenyltransferases

por Takahiro Mori, Lihan Zhang, Takayoshi Awakawa, Shotaro Hoshino, Masahiro Okada, Hiroyuki Morita, Ikuro Abe
Publicado 2016

Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis

por Yu Nakashima, Takahiro Mori, Hitomi Nakamura, Takayoshi Awakawa, Shotaro Hoshino, Miki Senda, Toshiya Senda, Ikuro Abe
Publicado 2018

Biosynthesis of helvolic acid and identification of an unusual C-4-demethylation process distinct from sterol biosynthesis

por Jian-Ming Lv, Dan Hu, Hao Gao, Tetsuo Kushiro, Takayoshi Awakawa, Guo-Dong Chen, Chuan-Xi Wang, Ikuro Abe, Xin-Sheng Yao
Publicado 2017

Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution

por Takayoshi Awakawa, Takuma Fujioka, Lihan Zhang, Shotaro Hoshino, Zhijuan Hu, Junko Hashimoto, Ikuko Kozone, Haruo Ikeda, Kazuo Shin-Ya, Wen Liu, Ikuro Abe
Publicado 2018

Biosynthetic pathway for furanosteroid demethoxyviridin and identification of an unusual pregnane side-chain cleavage

por Gao-Qian Wang, Guo-Dong Chen, Sheng-Ying Qin, Dan Hu, Takayoshi Awakawa, Shao-Yang Li, Jian-Ming Lv, Chuan-Xi Wang, Xin-Sheng Yao, Ikuro Abe, Hao Gao
Publicado 2018

Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation

por Yudai Matsuda, Tongxuan Bai, Christopher B. W. Phippen, Christina S. Nødvig, Inge Kjærbølling, Tammi C. Vesth, Mikael R. Andersen, Uffe H. Mortensen, Charlotte H. Gotfredsen, Ikuro Abe, Thomas O. Larsen
Publicado 2018

Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases

por Haibing He, Guangkai Bian, Corey J. Herbst-Gervasoni, Takahiro Mori, Stephen A. Shinsky, Anwei Hou, Xin Mu, Minjian Huang, Shu Cheng, Zixin Deng, David W. Christianson, Ikuro Abe, Tiangang Liu
Publicado 2020

C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes

por Takahiro Mori, Takuto Kumano, Haibing He, Satomi Watanabe, Miki Senda, Toshio Moriya, Naruhiko Adachi, Sanae Hori, Yuzu Terashita, Masato Kawasaki, Yoshiteru Hashimoto, Takayoshi Awakawa, Toshiya Senda, Ikuro Abe, Michihiko Kobayashi
Publicado 2021

Identification and characterization of N9-methyltransferase involved in converting caffeine into non-stimulatory theacrine in tea

por Yue-Hong Zhang, Yi-Fang Li, Yongjin Wang, Li Tan, Zhi-Qin Cao, Chao Xie, Guo Xie, Hai-Biao Gong, Wan-Yang Sun, Shu-Hua Ouyang, Wen-Jun Duan, Xiaoyun Lu, Ke Ding, Hiroshi Kurihara, Dan Hu, Zhi-Min Zhang, Ikuro Abe, Rong-Rong He
Publicado 2020