Rbpj expression in regulatory T cells is critical for restraining TH2 responses

Rbpj expression in regulatory T cells is critical for restraining TH2 responses

Transcriptional regulator Rbpj is involved in T-helper subset differentiation. Here the authors show that expression of Rbpj in regulatory T cells is required to both regulate TH2 responses and regulate Treg TH2 differentiation potential.

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Autores principales: Michael Delacher, Christian Schmidl, Yonatan Herzig, Minka Breloer, Wiebke Hartmann, Fabian Brunk, Danny Kägebein, Ulrike Träger, Ann-Cathrin Hofer, Sebastian Bittner, Dieter Weichenhan, Charles D. Imbusch, Agnes Hotz-Wagenblatt, Thomas Hielscher, Achim Breiling, Giuseppina Federico, Hermann-Josef Gröne, Roland M. Schmid, Michael Rehli, Jakub Abramson, Markus Feuerer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
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Acceso en línea:https://doaj.org/article/f8c425dfd10a45c698bf9c4a6526c87e
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https://doaj.org/article/f8c425dfd10a45c698bf9c4a6526c87e

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