Rbpj expression in regulatory T cells is critical for restraining TH2 responses
Transcriptional regulator Rbpj is involved in T-helper subset differentiation. Here the authors show that expression of Rbpj in regulatory T cells is required to both regulate TH2 responses and regulate Treg TH2 differentiation potential.
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Nature Portfolio
2019
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oai:doaj.org-article:f8c425dfd10a45c698bf9c4a6526c87e2021-12-02T17:31:37ZRbpj expression in regulatory T cells is critical for restraining TH2 responses10.1038/s41467-019-09276-w2041-1723https://doaj.org/article/f8c425dfd10a45c698bf9c4a6526c87e2019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09276-whttps://doaj.org/toc/2041-1723Transcriptional regulator Rbpj is involved in T-helper subset differentiation. Here the authors show that expression of Rbpj in regulatory T cells is required to both regulate TH2 responses and regulate Treg TH2 differentiation potential.Michael DelacherChristian SchmidlYonatan HerzigMinka BreloerWiebke HartmannFabian BrunkDanny KägebeinUlrike TrägerAnn-Cathrin HoferSebastian BittnerDieter WeichenhanCharles D. ImbuschAgnes Hotz-WagenblattThomas HielscherAchim BreilingGiuseppina FedericoHermann-Josef GröneRoland M. SchmidMichael RehliJakub AbramsonMarkus FeuererNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-20 (2019) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Michael Delacher Christian Schmidl Yonatan Herzig Minka Breloer Wiebke Hartmann Fabian Brunk Danny Kägebein Ulrike Träger Ann-Cathrin Hofer Sebastian Bittner Dieter Weichenhan Charles D. Imbusch Agnes Hotz-Wagenblatt Thomas Hielscher Achim Breiling Giuseppina Federico Hermann-Josef Gröne Roland M. Schmid Michael Rehli Jakub Abramson Markus Feuerer Rbpj expression in regulatory T cells is critical for restraining TH2 responses |
| description |
Transcriptional regulator Rbpj is involved in T-helper subset differentiation. Here the authors show that expression of Rbpj in regulatory T cells is required to both regulate TH2 responses and regulate Treg TH2 differentiation potential. |
| format |
article |
| author |
Michael Delacher Christian Schmidl Yonatan Herzig Minka Breloer Wiebke Hartmann Fabian Brunk Danny Kägebein Ulrike Träger Ann-Cathrin Hofer Sebastian Bittner Dieter Weichenhan Charles D. Imbusch Agnes Hotz-Wagenblatt Thomas Hielscher Achim Breiling Giuseppina Federico Hermann-Josef Gröne Roland M. Schmid Michael Rehli Jakub Abramson Markus Feuerer |
| author_facet |
Michael Delacher Christian Schmidl Yonatan Herzig Minka Breloer Wiebke Hartmann Fabian Brunk Danny Kägebein Ulrike Träger Ann-Cathrin Hofer Sebastian Bittner Dieter Weichenhan Charles D. Imbusch Agnes Hotz-Wagenblatt Thomas Hielscher Achim Breiling Giuseppina Federico Hermann-Josef Gröne Roland M. Schmid Michael Rehli Jakub Abramson Markus Feuerer |
| author_sort |
Michael Delacher |
| title |
Rbpj expression in regulatory T cells is critical for restraining TH2 responses |
| title_short |
Rbpj expression in regulatory T cells is critical for restraining TH2 responses |
| title_full |
Rbpj expression in regulatory T cells is critical for restraining TH2 responses |
| title_fullStr |
Rbpj expression in regulatory T cells is critical for restraining TH2 responses |
| title_full_unstemmed |
Rbpj expression in regulatory T cells is critical for restraining TH2 responses |
| title_sort |
rbpj expression in regulatory t cells is critical for restraining th2 responses |
| publisher |
Nature Portfolio |
| publishDate |
2019 |
| url |
https://doaj.org/article/f8c425dfd10a45c698bf9c4a6526c87e |
| work_keys_str_mv |
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| _version_ |
1718380591064285184 |