Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination
The epidermis is a multi-layered epithelium formed by the differentiation of basal cells and movement into suprabasal layers. Here the authors define a role for the desmosomal cadherin desmoglein-1 in promoting the delamination of basal cells by remodeling the actin cytoskeleton through interactions...
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Auteurs principaux: | , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2018
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Accès en ligne: | https://doaj.org/article/f8d863c46db64eadbafdd04712ce57e4 |
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