Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes

Summary: Internalized and ubiquitinated signaling receptors are silenced by their intraluminal budding into multivesicular bodies aided by the endosomal sorting complexes required for transport (ESCRT) machinery. HD-PTP, an ESCRT protein, forms complexes with ESCRT-0, -I and -III proteins, and binds...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jalal M. Kazan, Guillaume Desrochers, Claire E. Martin, Hyeonju Jeong, Dmitri Kharitidi, Pirjo M. Apaja, Ariel Roldan, Nicole St. Denis, Anne-Claude Gingras, Gergely L. Lukacs, Arnim Pause
Format: article
Langue:EN
Publié: Elsevier 2021
Sujets:
Q
Accès en ligne:https://doaj.org/article/f8eb2fe20c114718a6151e5c0fe42afc
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!