Identification of a 57S translation complex containing closed-loop factors and the 60S ribosome subunit

Abstract In eukaryotic translation the 60S ribosome subunit has not been proposed to interact with mRNA or closed-loop factors eIF4E, eIF4G, and PAB1. Using analytical ultracentrifugation with fluorescent detection system, we have identified a 57S translation complex that contains the 60S ribosome,...

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Autores principales: Clyde L. Denis, Thomas M. Laue, Xin Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f913d2dae08f435f983fd4a9a50939cb
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