Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy

The endothelial glucocorticoid receptor plays a key role in the regulation of many diseases, including diabetes. Loss of this receptor results in accelerated renal fibrosis, a heightened inflammatory milieu, augmented Wnt signaling and suppression of fatty acid oxidation in diabetic kidneys.

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Autores principales: Swayam Prakash Srivastava, Han Zhou, Ocean Setia, Bing Liu, Keizo Kanasaki, Daisuke Koya, Alan Dardik, Carlos Fernandez-Hernando, Julie Goodwin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f93663ef9d3e4bd39f4587ef786d5886
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