Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy
The endothelial glucocorticoid receptor plays a key role in the regulation of many diseases, including diabetes. Loss of this receptor results in accelerated renal fibrosis, a heightened inflammatory milieu, augmented Wnt signaling and suppression of fatty acid oxidation in diabetic kidneys.
Guardado en:
Autores principales: | Swayam Prakash Srivastava, Han Zhou, Ocean Setia, Bing Liu, Keizo Kanasaki, Daisuke Koya, Alan Dardik, Carlos Fernandez-Hernando, Julie Goodwin |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f93663ef9d3e4bd39f4587ef786d5886 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Deficiency in catechol-o-methyltransferase is linked to a disruption of glucose homeostasis in mice
por: Megumi Kanasaki, et al.
Publicado: (2017) -
<i>NR3C1</i> Glucocorticoid Receptor Gene Polymorphisms Are Associated with Membranous and IgA Nephropathies
por: Michał Pac, et al.
Publicado: (2021) -
Artificial DnaJ Protein for protein production and conformational diseases
por: Akinori Hishiya, et al.
Publicado: (2017) -
Assessment of endothelial function and arterial rigidity in patients with type 1 diabetes at different stages of diabetic nephropathy
por: Evgenia Pavlovna Kosobyan, et al.
Publicado: (2011) -
Aminophylline restores glucocorticoid sensitivity in a guinea pig model of sudden sensorineural hearing loss induced by lipopolysaccharide
por: Qiong-Qiong Zhou, et al.
Publicado: (2017)