Reconstruction of cellular signal transduction networks using perturbation assays and linear programming.

Perturbation experiments for example using RNA interference (RNAi) offer an attractive way to elucidate gene function in a high throughput fashion. The placement of hit genes in their functional context and the inference of underlying networks from such data, however, are challenging tasks. One of t...

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Autores principales: Bettina Knapp, Lars Kaderali
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/f9449206da6142209436d75ab561ace2
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