Reconstruction of cellular signal transduction networks using perturbation assays and linear programming.
Perturbation experiments for example using RNA interference (RNAi) offer an attractive way to elucidate gene function in a high throughput fashion. The placement of hit genes in their functional context and the inference of underlying networks from such data, however, are challenging tasks. One of t...
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2013
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Accès en ligne: | https://doaj.org/article/f9449206da6142209436d75ab561ace2 |
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