Metabolic network topology reveals transcriptional regulatory signatures of type 2 diabetes.

Type 2 diabetes mellitus (T2DM) is a disorder characterized by both insulin resistance and impaired insulin secretion. Recent transcriptomics studies related to T2DM have revealed changes in expression of a large number of metabolic genes in a variety of tissues. Identification of the molecular mech...

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Autores principales: Aleksej Zelezniak, Tune H Pers, Simão Soares, Mary Elizabeth Patti, Kiran Raosaheb Patil
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/f98d720481d1419c8e5fc03d50c89ed7
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