Fluorescent RNA cytosine analogue – an internal probe for detailed structure and dynamics investigations

Abstract The bright fluorescent cytosine analogue tCO stands out among fluorescent bases due to its virtually unquenched fluorescence emission in duplex DNA. However, like most reported base analogues, it has not been thoroughly characterized in RNA. We here report on the first synthesis and RNA-inc...

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Auteurs principaux: Anders Foller Füchtbauer, Søren Preus, Karl Börjesson, Scott A. McPhee, David M. J. Lilley, L. Marcus Wilhelmsson
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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R
Q
Accès en ligne:https://doaj.org/article/f9924c7b2eb845ad804425dc82e6bff6
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