The Gut Microbiota Metabolite Urolithin B Improves Cognitive Deficits by Inhibiting Cyt C-Mediated Apoptosis and Promoting the Survival of Neurons Through the PI3K Pathway in Aging Mice

Background: Despite considerable advances in pharmacotherapy, more effective therapeutic interventions for aging-related neurodegenerative disorders (NDs), such as Alzheimer’s disease (AD), remain limited. Urolithin B (UB), one of the major subcategories of urolithins (microbiota metabolites) found...

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Détails bibliographiques
Auteurs principaux: Peng Chen, Fuchao Chen, Jiexin Lei, Gaohua Wang, Benhong Zhou
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
Sujets:
UB
Accès en ligne:https://doaj.org/article/f998bb5703aa49e3bdbf7aa54a5a598e
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