Effects of reduced weight maintenance and leptin repletion on functional connectivity of the hypothalamus in obese humans.

Treating obesity has proven to be an intractable challenge, in part, due to the difficulty of maintaining reduced weight. In our previous studies of in-patient obese subjects, we have shown that leptin repletion following a 10% or greater weight loss reduces many of the metabolic (decreased energy e...

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Autores principales: William Hinkle, Michael Cordell, Rudy Leibel, Michael Rosenbaum, Joy Hirsch
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/f9b1e9bb115e40d5b3fb6051bed4b96a
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