The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones
R2TP is an HSP90 co-chaperone composed of an RPAP3-PIH1D1 heterodimer, which binds two essential AAA+ ATPases RUVBL1/RUVBL2. Here authors use a structural approach to study RPAP3 and find an RPAP3-like protein (SPAG1) which also forms a co-chaperone complex with PIH1D2 and RUVBL1/2 enriched in testi...
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Auteurs principaux: | , , , , , , , , , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2018
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Accès en ligne: | https://doaj.org/article/f9bce095aa2a4c49a49a7a66e4c6ecf6 |
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