The combination therapy of oncolytic HSV-1 armed with anti-PD-1 antibody and IL-12 enhances anti-tumor efficacy
Cancer immunotherapy is a new therapeutic strategy for cancer treatment that targets tumors by improving or restoring immune system function. Therapies targeting immune checkpoint molecules have exerted potent anti-tumor effects and prolonged the overall survival rate of patients. However, only a sm...
Saved in:
Main Authors: | Xin Xie, Jingwen Lv, Wei Zhu, Chao Tian, Jingfeng Li, Jiajia Liu, Hua Zhou, Chunyang Sun, Zongfeng Hu, Xiaopeng Li |
---|---|
Format: | article |
Language: | EN |
Published: |
Elsevier
2022
|
Subjects: | |
Online Access: | https://doaj.org/article/fa02f758bc344d9cb6d0c4f44a8890f4 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Oncolytic Viruses: Newest Frontier for Cancer Immunotherapy
by: Masmudur M. Rahman, et al.
Published: (2021) -
Oncolytic Virotherapy
Published: (2016) -
SELECTED ASPECTS OF ALLO- AND XENOGRAFT MODEL APPLICATIONS FOR DEVELOPING NOVEL ANTI-CANCER VACCINES AND ONCOLYTIC VIRUSES
by: T. S. Nepomnyashchikh, et al.
Published: (2019) -
USP18 and USP20 restrict oHSV-1 replication in resistant human oral squamous carcinoma cell line SCC9 and affect the viability of SCC9 cells
by: Ruitao Lu, et al.
Published: (2021) -
Single-cell RNA sequencing reveals a strong connection between Gadd45g upregulation and oncolytic HSV infection in tumor tissue
by: Divya Ravirala, et al.
Published: (2021)