A systems approach reveals distinct metabolic strategies among the NCI-60 cancer cell lines.
The metabolic phenotype of cancer cells is reflected by the metabolites they consume and by the byproducts they release. Here, we use quantitative, extracellular metabolomic data of the NCI-60 panel and a novel computational method to generate 120 condition-specific cancer cell line metabolic models...
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Main Authors: | Maike K Aurich, Ronan M T Fleming, Ines Thiele |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2017
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Online Access: | https://doaj.org/article/fa1b987fe15c4f63b5c4ad46c7bdbee5 |
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