Network-based prediction of drug combinations

Combination therapy holds great promise, but discovery remains challenging. Here, the authors propose a method to identify efficacious drug combinations for specific diseases, and find that successful combinations tend to target separate neighbourhoods of the disease module in the human interactome.

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Auteurs principaux: Feixiong Cheng, István A. Kovács, Albert-László Barabási
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/fa2350977aa946a497b6fc542fe19dad
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