Functionalization of remote C(sp3)-H bonds enabled by copper-catalyzed coupling of O-acyloximes with terminal alkynes
Sonogashira cross-coupling is a powerful strategy to prepare functionalized internal alkynes. Here, the authors report a domino sequence for the generation of γ-/δ-alkynyl nitriles and γ-alkynyl ketones from the coupling of terminal alkynes with O-acyloximes derived from cycloalkanones and acylic ke...
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2020
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/fa2abf7032de466aab33b7098f4cbaf9 |
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