Catalytic enantioselective reductive domino alkyl arylation of acrylates via nickel/photoredox catalysis

Enantioenriched α-aryl propionic acids are an important class of nonsteroidal anti-inflammatory medications. Here the authors use a visible-light-promoted photoredox/nickel catalyzed method to form such compunds via a three-component alkyl arylation of acrylates.

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Autores principales:	Pengcheng Qian, Haixing Guan, Yan-En Wang, Qianqian Lu, Fan Zhang, Dan Xiong, Patrick J. Walsh, Jianyou Mao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/fa45e986c72b46ca9096bd04bd38fc39
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spelling	oai:doaj.org-article:fa45e986c72b46ca9096bd04bd38fc392021-11-21T12:34:47ZCatalytic enantioselective reductive domino alkyl arylation of acrylates via nickel/photoredox catalysis10.1038/s41467-021-26794-82041-1723https://doaj.org/article/fa45e986c72b46ca9096bd04bd38fc392021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26794-8https://doaj.org/toc/2041-1723Enantioenriched α-aryl propionic acids are an important class of nonsteroidal anti-inflammatory medications. Here the authors use a visible-light-promoted photoredox/nickel catalyzed method to form such compunds via a three-component alkyl arylation of acrylates.Pengcheng QianHaixing GuanYan-En WangQianqian LuFan ZhangDan XiongPatrick J. WalshJianyou MaoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Pengcheng Qian Haixing Guan Yan-En Wang Qianqian Lu Fan Zhang Dan Xiong Patrick J. Walsh Jianyou Mao Catalytic enantioselective reductive domino alkyl arylation of acrylates via nickel/photoredox catalysis
description	Enantioenriched α-aryl propionic acids are an important class of nonsteroidal anti-inflammatory medications. Here the authors use a visible-light-promoted photoredox/nickel catalyzed method to form such compunds via a three-component alkyl arylation of acrylates.
format	article
author	Pengcheng Qian Haixing Guan Yan-En Wang Qianqian Lu Fan Zhang Dan Xiong Patrick J. Walsh Jianyou Mao
author_facet	Pengcheng Qian Haixing Guan Yan-En Wang Qianqian Lu Fan Zhang Dan Xiong Patrick J. Walsh Jianyou Mao
author_sort	Pengcheng Qian
title	Catalytic enantioselective reductive domino alkyl arylation of acrylates via nickel/photoredox catalysis
title_short	Catalytic enantioselective reductive domino alkyl arylation of acrylates via nickel/photoredox catalysis
title_full	Catalytic enantioselective reductive domino alkyl arylation of acrylates via nickel/photoredox catalysis
title_fullStr	Catalytic enantioselective reductive domino alkyl arylation of acrylates via nickel/photoredox catalysis
title_full_unstemmed	Catalytic enantioselective reductive domino alkyl arylation of acrylates via nickel/photoredox catalysis
title_sort	catalytic enantioselective reductive domino alkyl arylation of acrylates via nickel/photoredox catalysis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/fa45e986c72b46ca9096bd04bd38fc39
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Catalytic enantioselective reductive domino alkyl arylation of acrylates via nickel/photoredox catalysis

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